IMLYGIC® Has Special STORAGE AND HANDLING Requirements1

This section offers information and resources related to the logistics of bringing IMLYGIC® (talimogene laherparepvec) to your practice or institution. Please be sure to fully review this information to ensure you understand the special ordering, shipping, storage, and handling requirements of IMLYGIC®.

Storage and handling video for IMLYGIC®

This step-by-step video provides an example of what to do when you receive a shipment of IMLYGIC®, including instructions on storage and safe handling requirements. This video does not replace the Prescribing Information. Please review the Prescribing Information before handling IMLYGIC®.

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Storage and handling video
This step-by-step video describes what to do when you receive a shipment of IMLYGIC®, including instructions on storage and safe handling requirements.
This step-by-step video describes what to do when you receive a shipment of IMLYGIC®, including instructions on storage and safe handling requirements.

Consider options for ordering and storing IMLYGIC®

PROCUREMENT

Keep in stock.

  • For longer-term storage, IMLYGIC® must be stored in a freezer that is able to maintain temperature at -90°C to -70°C.1 If an ultra-low freezer is not available to you, see details below about the IMLYGIC® Freezer Program.
  • Before placing the order, it is important to determine the number of IMLYGIC® vials that will be kept on hand. Up to 4 vials can be used per patient per treatment visit for all injectable lesions combined.1

OR

Use just-in-time ordering.

  • IMLYGIC® can be stored in its shipping container as long as the ordered product is intended for use within 96 hours after the shipment has been sealed for delivery, per expiration time on the side of the container.2
  • Before placing the order for just-in-time delivery it is important to determine the number of IMLYGIC® vials that will be used. Up to 4 vials per patient per treatment visit for all injectable lesions combined.1
  • To prevent treatment delays, timing of product delivery should be coordinated with scheduling of the patient visit for IMLYGIC® administration. See the delivery schedule below for more information.

STORAGE

Store frozen in an ultra-low freezer.

  • IMLYGIC® should be protected from light and stored in the carton until use.1
  • Thaw IMLYGIC® immediately prior to administration.1
  • Do not draw IMLYGIC® into a syringe until immediately prior to administration.1

IMLYGIC® FREEZER PROGRAM

For institutions that need an ultra-low freezer for storing IMLYGIC®, Amgen can provide access to one when you purchase IMLYGIC®. For more information, call 1-866-IMLYGIC (465-9442); choose Option 1 for Health Care Providers, then Option 2 for Ordering.

OR

Store frozen in the original IMLYGIC® shipping container for up to 96 hours.2

  • The IMLYGIC® shipping container will hold the correct storage temperatures for up to 96 hours after being sealed for delivery. This expiration time is printed on the container.2
  • IMLYGIC® should be protected from light and stored in the carton until use.1
  • Thaw IMLYGIC® immediately prior to administration.1
  • Do not draw IMLYGIC® into a syringe until immediately prior to administration.1

For additional storage and handling information, including developing order sets for your institution, creating safeguard rules, and thawing and dispensing IMLYGIC®, please use the downloadable checklists and guides located on this page or watch the step-by-step video above.

IMLYGIC® delivery schedule

Because of its special properties and storage requirements, IMLYGIC® is shipped on a fixed delivery schedule for coordination with patient scheduling. You can plan to receive your orders of IMLYGIC® based on the following calendar:

Order on Mon, Tue, Wed, Thu, and Fri, and receive on Wed, Thu, Fri, Tue, and Tue, respectively

Order on Mon, Tue, Wed, Thu, and Fri, and receive on Wed, Thu, Fri, Tue, and Tue, respectively

  • If your facility does not have access to a -80°C freezer, please schedule treatments from Tuesday afternoon through Friday, as deliveries do not take place on Monday.
  • Amgen does not process orders on the following holidays: New Year’s Day, Martin Luther King Day, Memorial Day, Independence Day, Labor Day, Thanksgiving Day, the day after Thanksgiving, Christmas Eve, Christmas Day.
  • IMLYGIC® may only be ordered through an authorized distributor, who will then coordinate the shipment with AMGEN. To see a list of authorized distributors, please download the IMLYGIC® Product Ordering Guide.

Download the details

IMLYGIC® Clinical Overview and Handling Guide

Use this instructional guide to review efficacy, dosing, and administration details, and to get information about integrating IMLYGIC® into your practice.

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IMLYGIC® Product Ordering Guide

IMLYGIC® is shipped from select authorized specialty distributors—use this guide to find a qualified distributor. Also find information on ordering options, the order and delivery schedule, product storage, and the IMLYGIC® freezer program.

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IMLYGIC® Delivery Schedule

Because of its special properties and storage requirements, IMLYGIC® is shipped on a fixed delivery schedule for coordination with patient scheduling. Download and print a copy of the schedule here for convenience.

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IMLYGIC® Operational Planning Checklist

Get some key product information, including packaging details, information on ordering IMLYGIC®, and storage and handling requirements.

The Prescribing Information provides all of the requirements for handling IMLYGIC®. This Checklist is not intended to serve as a replacement for the Prescribing Information.

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Before using IMLYGIC® it is important to review the Prescribing Information. IMLYGIC® requires special storage conditions. Please see the Prescribing Information (section 2) for details on preparation and handling, including guidance on thawing and storage of IMLYGIC® vials.

IMLYGIC® coding and billing information

To learn about billing and coding considerations for IMLYGIC®, please review the Hospital Outpatient Billing Information Sheet for IMLYGIC® and the Physician Office Billing Information Sheet for IMLYGIC®.

Register IMLYGIC® customers

Orders of IMLYGIC® are managed directly by Amgen. Please complete a Customer Registration Profile at the IMLYGIC® Customer Registration Page to ensure that Amgen has the information needed for processing your orders.

REFERENCES

  1. IMLYGIC® (talimogene laherparepvec) Prescribing Information, BioVex, Inc., a subsidiary of Amgen Inc.
  2. Data on file, Amgen.